Stem Cell Apheresis in Gurgaon & Faridabad
Pioneering precision peripheral blood stem cell (PBSC) harvesting, therapeutic plasma exchange, and leukapheresis using cutting-edge automated cell separators with complete donor comfort and safety.
Non-Surgical
No General Anesthesia Needed
High Yield
Flow Cytometry CD34+ Tracking
Safe Return
99% RBCs & Plasma Conserved
Same Day
Outpatient Harvesting Sessions
Specialized Apheresis Modalities Offered
Using state-of-the-art continuous flow centrifuges to isolate exact cellular fractions with maximum viability.
Peripheral Blood Stem Cell (PBSC) Collection
Automated collection of healthy blood-forming hematopoietic stem cells (CD34+) from autologous patients or matched allogeneic donors for transplantation without requiring marrow surgery.
Therapeutic Plasma Exchange (TPE)
Separation and removal of disease-causing circulating autoantibodies, immune complexes, or toxic paraproteins, replaced immediately with donor albumin or fresh frozen plasma.
Therapeutic Cytoreduction (Leukapheresis)
Emergency high-speed extraction of dangerously elevated white blood cells or platelets in newly diagnosed acute leukemia (hyperleukocytosis) or essential thrombocythemia.
Indications Treated with Apheresis Technologies
Providing essential support for cellular transplant programs and critical hematological emergencies.
Cellular Transplants & Immunotherapy Harvesting
- Autologous PBSC Harvesting: Multiple Myeloma, Relapsed Hodgkin & Non-Hodgkin Lymphoma, and select solid tumors prior to high-dose chemotherapy.
- Allogeneic Donor Harvesting: Fully matched sibling donors, voluntary registry donors (DATRI/DKMS), and Haploidentical family donors.
- T-Cell Apheresis for CAR-T Therapy: Specialized collection of autologous T-lymphocytes for genetic engineering into living CAR-T therapies.
- Donor Lymphocyte Infusion (DLI): Collecting mature donor immune cells to treat post-transplant minimal residual disease or leukemia relapse.
Therapeutic Exchanges & Acute Hematology
- Thrombotic Thrombocytopenic Purpura (TTP): Emergency plasma exchange to replenish ADAMTS13 activity and stop microvascular thrombosis.
- Guillain-Barré Syndrome (GBS) & Myasthenia Gravis: Fast antibody removal to restore neurological motor functions.
- Hyperleukocytosis in Acute Leukemia: Rapid leukoreduction to avoid fatal pulmonary leukostasis and cerebral hemorrhage.
- Severe ABO-Incompatible Transplants: Antibody removal protocols enabling successful mismatched organ and marrow transplants.
The Stem Cell Apheresis Journey At Marengo Asia Hospitals
A supervised 4-phase protocol ensuring maximum cell yield with zero compromise on donor health.
Stem Cell Mobilization
4–5 days of G-CSF injections to gently release bone marrow stem cells into the bloodstream.
CD34+ Cell Monitoring
Flow cytometry blood count testing to pinpoint the optimal day for peak cell harvesting.
Automated Apheresis
3–4 hour comfortable session where stem cells are separated and collected via a closed sterile kit.
Quality & Cryopreservation
Cell enumeration, sterility assay, and controlled-rate freezing in liquid nitrogen (-196°C).
Liquid Nitrogen Cryopreservation & Controlled-Rate Freezing
Harvested stem cell grafts are immediately evaluated in our specialized cellular processing laboratory. Using precise multi-color Flow Cytometry, we verify target CD34+ cell counts (ensuring optimal doses of >2–5 × 10⁶ CD34+ cells/kg for rapid engraftment). For autologous transplant recipients, stem cells are treated with DMSO cryoprotectant and cryopreserved in liquid nitrogen vapor tanks (-196°C) for safe, long-term storage until conditioning chemotherapy is complete.
Frequently Asked Questions on Stem Cell Apheresis
How does Peripheral Blood Stem Cell (PBSC) collection differ from Bone Marrow Aspiration?
In traditional bone marrow harvesting, a surgical procedure under general anesthesia is required to extract liquid marrow from the pelvic bone with multiple needle punctures. In PBSC Apheresis, no surgery is needed. Stem cells are mobilized into the blood using G-CSF growth factor injections and collected painlessly from a standard vein cannula or central line using an automated cell separator, allowing donors to resume normal routines the very next day.
What patient assistance and special programs are available for apheresis procedures?
To ensure essential apheresis and harvesting therapies are seamless, Marengo Asia Hospitals offers:
• Patient Funding Support: Dedicated desk assistance for cashless insurance approvals and medical welfare trust claims.
• Registry Donor Welfare: Comprehensive logistical and medical support for non-related voluntary stem cell donors (DATRI, DKMS registries).
• Compassionate Access to Mobilizers: Assistance with accessing advanced, targeted mobilizers like Plerixafor for difficult-to-mobilize myeloma and lymphoma patients.
Are there any side effects during or after the stem cell harvesting procedure?
PBSC apheresis is very safe. During mobilization, donors may feel mild, temporary bone achiness from G-CSF injections, which resolves easily with paracetamol. During the apheresis session, a mild tingling sensation around the lips or fingers may occur due to temporary citrate-induced low calcium levels, which is quickly prevented and treated with oral or intravenous calcium supplements.
Need Guidance on Stem Cell Harvesting or Apheresis?
Connect with our Apheresis Specialists and Lead Hematologists at Marengo Asia Hospitals, Gurugram & Faridabad for personalized clinical consultation and donor evaluations.
